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Cycloheximide

Translation inhibitor

Product Specifications

Background

Selective inhibitor of eukaryotic protein synthesis blocking tRNA binding and release from ribosomes. Induces apoptosis in a variety of transformed and normal cell lines, including T-cells.

CAS Number

66-81-9

Product Name Alternative

4-{ (2R) -2-[ (1S,3S,5S) -3,5-Dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}-2,6-piperidinedione

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cancer | Apoptosis

Purity

>98%

Weight

1

Format

White solid

Solubility

Soluble to 50 mM in Ethanol and 25 mM in water

Molecular Formula

C15H23NO4

Molecular Weight

281.35

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Obrig T.G., et al. (1971) J Biol Chem. 246:174.

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