Ionomycin
Ca2+ ionophore
Product Specifications
Background
Ionomycin is a calcium ionophore used in research to raise the intracellular level of calcium and as a tool to understand calcium transport across biological membranes. It is also used to stimulare the intracellular production of the cytokines interferon, perforin, IL-2 and IL-4. It is more specific than A23187.
CAS Number
56092-81-0
Product Name Alternative
(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S) -11,19,21-Trihydroxy-22-{ (2S,2'R,5S,5'S) -5'-[ (1R) -1-hydroxyethyl]-2,5'-dimethyloctahydro-2,2'-bifuran-5-yl}-4,6,8,12,14,18,20-heptamethyl-9-oxo-10,16-docosadi enoic acid, Ionomycin calcium salt
UNSPSC
41116105
Type
Inducer
Source
Synthetic
Field of Research
Cancer | Apoptosis
Purity
>98%
Weight
0.005
Format
Colorless Solid
Solubility
Soluble to 10 mM in ethanol and to 10 mM in DMSO
Molecular Formula
C41H70O9
Molecular Weight
709.01
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Holmes A.G. Watt M.J., Carey A.L. And Febbraio M.A. (2004) Metabolism. 53(11): 1492-1495.
2. Abramov A.Y., Duchen M.R. (2003) Cell Calcium. 33(2): 101-112.
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