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Ionomycin

Ca2+ ionophore

Product Specifications

Background

Ionomycin is a calcium ionophore used in research to raise the intracellular level of calcium and as a tool to understand calcium transport across biological membranes. It is also used to stimulare the intracellular production of the cytokines interferon, perforin, IL-2 and IL-4. It is more specific than A23187.

CAS Number

56092-81-0

Product Name Alternative

(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S) -11,19,21-Trihydroxy-22-{ (2S,2'R,5S,5'S) -5'-[ (1R) -1-hydroxyethyl]-2,5'-dimethyloctahydro-2,2'-bifuran-5-yl}-4,6,8,12,14,18,20-heptamethyl-9-oxo-10,16-docosadi enoic acid, Ionomycin calcium salt

UNSPSC

41116105

Type

Inducer

Source

Synthetic

Field of Research

Cancer | Apoptosis

Purity

>98%

Weight

0.005

Format

Colorless Solid

Solubility

Soluble to 10 mM in ethanol and to 10 mM in DMSO

Molecular Formula

C41H70O9

Molecular Weight

709.01

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Holmes A.G. Watt M.J., Carey A.L. And Febbraio M.A. (2004) Metabolism. 53(11): 1492-1495. 2. Abramov A.Y., Duchen M.R. (2003) Cell Calcium. 33(2): 101-112.

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