A23187
Ca2+ ionophore
Product Specifications
Background
A23187 is a mobile ion-carrier that forms stable complexes with divalent cations. It has antibiotic properties against gram positive bacteria and funghi. It also acts as divalent cation ionophore, that is used to increase intracellular calcium levels in intact cells (1). It also induces apoptosis in some cells and prevents it in others (2).
CAS Number
52665-69-7
Product Name Alternative
5- (Methylamino) -2- ({ (2S,3S,8S,9R,11R) -3,9,11-trimethyl-8-[ (2S) -1-oxo-1- (1H-pyrrol-2-yl) -2-propanyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl) -1,3-benzoxazole-4-carboxylic acid, A23187, Calcimycin
UNSPSC
41116105
Type
Inducer
Source
Synthetic
Field of Research
Cancer | Apoptosis
Purity
>98%
Weight
0.01
Format
White Solid
Solubility
Soluble to 10 mM in ethanol and to 50 mM in DMSO
Molecular Formula
C29H37N3O6
Molecular Weight
523.63
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Abbott B.J., et al. (1979) Antimicrob Agents Chemother. 16(6): 808-812. 2. http://a23187.4mg.com
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