PK-11195
Mitochondrial Benzodiazepine receptor ligand
Product Specifications
Background
PK-11195 is an isoquinoline carboxamide which binds selectively to the peripheral benzodiazepine receptor (PBR). It has a high affinity for the PBR in all species (1). It has also been successfully used in PET scans to visualize brain inflammation in patients with neuronal damage (2).
CAS Number
85532-75-8
Product Name Alternative
N-sec-Butyl-1- (2-chlorophenyl) -N-methyl-3-isoquinolinecarboxamide
UNSPSC
41116105
Type
Inducer
Source
Synthetic
Field of Research
Cancer | Apoptosis
Purity
>98%
Weight
0.025
Format
White Crystals
Solubility
Soluble to 75 mM in ethanol and to 100 mM in DMSO
Molecular Formula
C21H21CIN2O
Molecular Weight
352.86
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Pike V.W., et al. (1993) Nucl Med & Bio. 20(4): 503-525. 2. Buck J.R., et al. (2011) J Nucl Med. 52(1): 107-114.
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