Andrographolide
Apoptosis Inducer
Product Specifications
Background
Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata. Is has been shown to be effective against certain cancers, and is an effective purgative (1). It blocks T-cell proliferation to allogenic stimuli and the chemotactic migration of macrophages induced by complement (2, 3).
CAS Number
5508-58-7
Product Name Alternative
(3E) -4-Hydroxy-3-{2-[ (1R,4aS,6R,8aS) -6-hydroxy-5- (hydroxymethyl) -5,8a-dimethyl-2-methylenedecahydro-1-naphthalenyl]ethylidene}dihydro-2 (3H) -furanone
UNSPSC
41116105
Type
Inducer
Source
Synthetic
Field of Research
Cancer | Apoptosis
Purity
>98%
Weight
0.5
Format
Off-white Solid
Solubility
DMSO
Molecular Formula
C20H30O5
Molecular Weight
350.45
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Chakravarti R.N., Chakravarti D. (1951) Ind. Med Gaz. 86(3): 96-7.
2. Tsai H.R., et al. (2004) Eur J Pharmacol. 498: 45-52.
3. Rajagopal S., et al. (2003) J Exp. Ther. Oncol. 3: 147-158.
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