U-74389G

Lipid peroxidation blocker

Product Specifications

Background

U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It prevents organ damage in intestinal cold storage, preservation and reperfusion injury (1-4).

Product Name Alternative

21-{4-[2,6-Di(1-pyrrolidinyl)-4-pyrimidinyl]-1-piperazinyl}pregna-1,4,9(11)-triene-3,20-dione (2Z)-2-butenedioate (1:1)

UNSPSC

41116105

Source

Synthetic

Purity

>99%

Weight

0.5

Format

White Solid

Solubility

Soluble in 25 mg/ml DMSO, and in 20 mg/ml in ethanol; Insoluble in water

Molecular Formula

C37H50N6O2•C4H4O4

Molecular Weight

726.9

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Ishizaki N., et al. (1997) Transplantation. 63: 202-208. 2. Perna A.M., et al. (1996) Pharmacol Res. 34: 25-31. 3. Palma-Vargas J.M., et al. (1996) J Surg Res. 66: 131-137. 4. Shoskes D.A., Xie Y., Gonzalez-Cadavid N.F. Transplantation. 63: 495-500.