U-74389G
Lipid peroxidation blocker
Product Specifications
Background
U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It prevents organ damage in intestinal cold storage, preservation and reperfusion injury (1-4).
CAS Number
153190-29-5
Product Name Alternative
21-{4-[2,6-Di (1-pyrrolidinyl) -4-pyrimidinyl]-1-piperazinyl}pregna-1,4,9 (11) -triene-3,20-dione (2Z) -2-butenedioate (1:1)
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cancer | Apoptosis
Purity
>99%
Weight
0.1
Format
White Solid
Solubility
Soluble in 25 mg/ml DMSO, and in 20 mg/ml in ethanol; Insoluble in water
Molecular Formula
C37H50N6O2•C4H4O4
Molecular Weight
726.9
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Ishizaki N., et al. (1997) Transplantation. 63: 202-208.
2. Perna A.M., et al. (1996) Pharmacol Res. 34: 25-31.
3. Palma-Vargas J.M., et al. (1996) J Surg Res. 66: 131-137.
4. Shoskes D.A., Xie Y., Gonzalez-Cadavid N.F. Transplantation. 63: 495-500.
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