Piperlongumine
Apoptosis Inducer
Product Specifications
Background
Piperlongumine is a novel compound that exhibits a potential inhibitory effect on washed rabbit platelet aggregation induced by collagen, arachidonic acid and platelet activating factor, without any inhibiting effect on that induced by thrombin (1). It has recently been found to kill cancer cells by blocking the response that dissipates high oxidative stress and the resulting reactive oxygen species (ROS) generated, meanwhile sparing normal cells (2).
Product Name Alternative
1-[(2E)-3-(3,4,5-Trimethoxyphenyl)-2-propenoyl]-5,6-dihydro-2(1H)-pyridinone
UNSPSC
41116105
Source
Synthetic
Purity
>98%
Weight
0.1
Format
Cream Solid
Solubility
Soluble in 25 mg/ml DMSO
Molecular Formula
C17H19NO5
Molecular Weight
317.3
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Park B.S., et al. (2008) Phytother Res. 22(9): 1195-1199. 2. Raj L., et al. (2011) Nature. 475(7355): 231.
CAS Number
20069-09-4
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