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Piperlongumine

Apoptosis Inducer

Product Specifications

Background

Piperlongumine is a novel compound that exhibits a potential inhibitory effect on washed rabbit platelet aggregation induced by collagen, arachidonic acid and platelet activating factor, without any inhibiting effect on that induced by thrombin (1). It has recently been found to kill cancer cells by blocking the response that dissipates high oxidative stress and the resulting reactive oxygen species (ROS) generated, meanwhile sparing normal cells (2).

CAS Number

20069-09-4

Product Name Alternative

1-[ (2E) -3- (3,4,5-Trimethoxyphenyl) -2-propenoyl]-5,6-dihydro-2 (1H) -pyridinone

UNSPSC

41116105

Type

Inducer

Source

Synthetic

Field of Research

Cancer | Oxidative Stress

Purity

>98%

Weight

0.1

Format

Cream Solid

Solubility

Soluble in 25 mg/ml DMSO

Molecular Formula

C17H19NO5

Molecular Weight

317.3

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Park B.S., et al. (2008) Phytother Res. 22(9): 1195-1199. 2. Raj L., et al. (2011) Nature. 475(7355): 231.

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