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115-7C

Hsp70 Activator

Product Specifications

Background

115-7c activates Hsp70 ATPase turnover rate and promotes Hsp70 substrate refolding. It binds to the IIA subdomain of DnaK and promotes the DnaK-DnaJ complex. Equivalent with SW02.

Product Name Alternative

4-(5-((benzyloxy)carbonyl)-4-(2,4-dichlorophenyl)-6-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)butanoic acid, SWO2

UNSPSC

41116105

Source

Synthetic

Purity

>98%

Weight

0.005

Format

White solid

Solubility

Soluble in DMSO (20 mg/ml)

Molecular Formula

C23H22Cl2N2O5

Molecular Weight

477.34

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Wisen et al., (2010) ACS Chem. Biol., 5: 611-622. 2. Jinwal et al. (2009) J.Neurosci. 29:12079. 3. Chafekar et al. (2012) ACS Chem Biol. 7:1556. 4. Walter et al. (2011) J. Biol. Chem. 286:40486