What is the catalog number for Gamma Synuclein Pre-formed Fibrils?

The catalog number for Gamma Synuclein Pre-formed Fibrils is SPR-459E.

What sizes are available for Gamma Synuclein Pre-formed Fibrils?

Gamma Synuclein Pre-formed Fibrils is available in the following size(s): 5x 100 µg.

Is Gamma Synuclein Pre-formed Fibrils in stock?

Gamma Synuclein Pre-formed Fibrils is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Gamma Synuclein Pre-formed Fibrils?

Gamma Synuclein Pre-formed Fibrils is requires dry ice shipping.

Where can I find the safety data sheet (SDS/MSDS) for Gamma Synuclein Pre-formed Fibrils?

The safety data sheet for Gamma Synuclein Pre-formed Fibrils is available here: https://cdn.gentaur.com/products/400/4430714/msds/spr-459e.pdf.

Gamma Synuclein Pre-formed Fibrils

Human Recombinant Gamma Synuclein PFFs (Type 1)

Product Specifications

Background

Gamma synuclein is a neuronal protein found in peripheral and motor nerve systems. It has been implicated in the hippocampal axon pathology in Parkinson's Disease (1) . A change in the expression of gamma synuclein has been observed in the retina of patients with Alzheimer's disease (2) . Its expression in breast tumors is also a marker for tumor progression (3) .

Product Name Alternative

BCSG1 Aggregate Protein, Breast cancer specific gene 1 Aggregate Protein, Breast cancer specific Protein 1 Agreggates, Gamma-synuclein Aggregate Protein, Persyn Aggregate Protein, PRSN Aggregate Protein, SNCG Aggregate Protein, SR Aggregate Protein, Synoretin Aggregate Protein, Synuclein gamma Aggregate Protein, SYUG_HUMAN Aggregate Protein

UNSPSC

12352202

UN Code

Non-hazardous

Hazard Statement

Non-hazardous

Gene ID

6623

Swiss Prot

O76070

Accession Number

NP_003078.2

Cellular Locus

Cytoskeleton | Centrosome | Spindle | Perinuclear Region

Expression System

E. coli

Host

E. coli

Origin Species

Human

Target

Gamma Synuclein

Conjugation

No tag

Nature

Recombinant

Applications

WB | SDS-PAGE | In vivo assay | In vitro assay

Field of Research

Purification Method

Ion-exchange Purified

Purification

Ion-exchange Purified

Limit Of Detection

Certified >95% pure using SDS-PAGE analysis. Low endotoxin <5 EU/mL @ 2mg/mL.

Concentration

2 mg/ml

Purity

>95%

Weight

0.5

Length

Full length

Buffer

PBS pH 7.4

Molecular Weight

13.33 kDa

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For research use only.

Additionnal Information

For best results, sonicate immediately prior to use. Refer to the Neurodegenerative Protein Handling Instructions on our website, or the product datasheet for further information. Monomer source is catalog# SPR-407.

References & Citations

1. Nishioka K., et al. (2010) Arch Neurol. 67(8): 970-975. 2. Surgucheva I., Newell K.L., Burns J., Surguchov A. (2014) Acta Neuropathol Commun. 2: 132. 3. Bruening. W., et al. (2000) Cancer. 88(9): 2154-2163. 4. Mukaetova-Ladinska E.B., et al. (2008) Dement Geriatr Cogn Disord. 26(1): 32-42.

Shipping Conditions

Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.

Storage Conditions

-80ºC

Notes

Protein Length

Full length

Background Reference 01

1. Nishioka K., et al. (2010) Arch Neurol. 67 (8) : 970-975. 2. Surgucheva I., Newell K.L., Burns J., Surguchov A. (2014) Acta Neuropathol Commun. 2: 132. 3. Bruening. W., et al. (2000) Cancer. 88 (9) : 2154-2163. 4. Mukaetova-Ladinska E.B., et al. (2008) Dement Geriatr Cogn Disord. 26 (1) : 32-42.