4-Hydroxynonenal BSA Conjugate
Bovine Serum Albumin (BSA) modified with 4-Hydroxy nonenal (4-HNE)
Product Specifications
Background
4-Hydroxynonenal (4-HNE) BSA Conjugate is a widely used biomarker for lipid peroxidation and oxidative stress in the brain. 4-HNE is derived from omega-6 fatty acid oxidation and forms stable adducts with nucleophilic amino acids, disrupting protein function and cellular signaling. In neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and ALS, 4-HNE-modified proteins accumulate in affected brain regions, contributing to synaptic dysfunction, mitochondrial damage, and chronic inflammation. 4-HNE also activates pro-apoptotic pathways and impairs proteasomal degradation, exacerbating neuronal loss. The BSA conjugate enables precise quantification of 4-HNE adducts in tissue and serum samples, facilitating biomarker discovery and therapeutic evaluation in oxidative stress-driven neurodegeneration.
Product Name Alternative
4-Hydroxynonenal BSA Conjugate, 4-Hydroxy Nonenal (4-HNE) BSA Conjugate, 4-Hydroxy Nonenal BSA Conjugate, 4-HNE BSA Conjugate, 4-Hydroxy Nonenal-BSA Conjugate, 4-Hydroxy Nonenal (BSA) Conjugate, MG-BSA, MG-BSA Conjugate, 4-Hydroxy Nonenal-modified BSA, 4-Hydroxy Nonenal Bovine Serum Albumin Conjugate, 4-Hydroxy Nonenal-Bovine Serum Albumin Conjugate, 4-Hydroxy Nonenal (Bovine Serum Albumin) Conjugate, 4-Hydroxy Nonenal-modified Bovine Serum Albumin, 4-Hydroxy Nonenal-bovine serum albumin, HNE BSA Conjugate, 4-hydroxy-2-nonenal BSA Conjugate
UNSPSC
12352202
UN Code
Non-hazardous
Hazard Statement
Non-hazardous
Expression System
Synthetic
Host
Synthetic
Target
4-Hydroxynonenal BSA Conjugate
Conjugation
No tag
Applications
WB | ELISA
Field of Research
Cancer | Oxidative Stress | Lipid peroxidation
Purification Method
Filter Sterilized (0.2 µm)
Purification
Filter Sterilized (0.2 µm)
Limit Of Detection
Detectable in ELISA at ≥ 5 ng.
Concentration
Lot/batch specific. See included datasheet.
Purity
>98%
Weight
0.1
Buffer
PBS pH 7.4, 0.09% Sodium Azide
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For research use only.
Shipping Conditions
Blue Ice or 4ºC
Storage Conditions
-20ºC
Documents
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items