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4-Hydroxynonenal BSA Conjugate

Bovine Serum Albumin (BSA) modified with 4-Hydroxy nonenal (4-HNE)

Product Specifications

Background

4-Hydroxynonenal (4-HNE) BSA Conjugate is a widely used biomarker for lipid peroxidation and oxidative stress in the brain. 4-HNE is derived from omega-6 fatty acid oxidation and forms stable adducts with nucleophilic amino acids, disrupting protein function and cellular signaling. In neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and ALS, 4-HNE-modified proteins accumulate in affected brain regions, contributing to synaptic dysfunction, mitochondrial damage, and chronic inflammation. 4-HNE also activates pro-apoptotic pathways and impairs proteasomal degradation, exacerbating neuronal loss. The BSA conjugate enables precise quantification of 4-HNE adducts in tissue and serum samples, facilitating biomarker discovery and therapeutic evaluation in oxidative stress-driven neurodegeneration.

Product Name Alternative

4-Hydroxynonenal BSA Conjugate, 4-Hydroxy Nonenal (4-HNE) BSA Conjugate, 4-Hydroxy Nonenal BSA Conjugate, 4-HNE BSA Conjugate, 4-Hydroxy Nonenal-BSA Conjugate, 4-Hydroxy Nonenal (BSA) Conjugate, MG-BSA, MG-BSA Conjugate, 4-Hydroxy Nonenal-modified BSA, 4-Hydroxy Nonenal Bovine Serum Albumin Conjugate, 4-Hydroxy Nonenal-Bovine Serum Albumin Conjugate, 4-Hydroxy Nonenal (Bovine Serum Albumin) Conjugate, 4-Hydroxy Nonenal-modified Bovine Serum Albumin, 4-Hydroxy Nonenal-bovine serum albumin, HNE BSA Conjugate, 4-hydroxy-2-nonenal BSA Conjugate

UNSPSC

12352202

UN Code

Non-hazardous

Hazard Statement

Non-hazardous

Expression System

Synthetic

Host

Synthetic

Target

4-Hydroxynonenal BSA Conjugate

Conjugation

No tag

Applications

WB | ELISA

Field of Research

Cancer | Oxidative Stress | Lipid peroxidation

Purification Method

Filter Sterilized (0.2 µm)

Purification

Filter Sterilized (0.2 µm)

Limit Of Detection

Detectable in ELISA at ≥ 5 ng.

Concentration

Lot/batch specific. See included datasheet.

Purity

>98%

Weight

0.1

Buffer

PBS pH 7.4, 0.09% Sodium Azide

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For research use only.

Shipping Conditions

Blue Ice or 4ºC

Storage Conditions

-20ºC

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