4-Hydroxy-2-hexenal BSA Conjugate
Bovine Serum Albumin (BSA) modified with 4-Hydroxy-2-hexenal (4-HHE)
Product Specifications
Background
4-Hydroxy-2-hexenal (HHE) BSA Conjugate is a lipid peroxidation marker used to study oxidative damage in neural tissues. HHE is generated from the oxidation of omega-3 polyunsaturated fatty acids and forms covalent adducts with proteins, altering their structure and function. In the nervous system, HHE accumulation is associated with mitochondrial dysfunction, synaptic impairment, and neuroinflammation. Elevated HHE levels have been observed in neurodegenerative conditions such as Alzheimer’s disease and ischemic brain injury, where they contribute to neuronal apoptosis and glial activation. The BSA-conjugated form allows for sensitive detection of HHE-modified proteins in immunoassays and histological studies. It supports research into the molecular mechanisms of oxidative stress and the development of antioxidant therapies targeting lipid peroxidation in neurodegeneration.
Product Name Alternative
4-Hydroxy-2-hexenal (4-HHE) BSA Conjugate, 4-Hydroxy-2-hexenal BSA Conjugate, 4-HHE BSA Conjugate, 4-Hydroxy-2-hexenal-BSA Conjugate, 4-Hydroxy-2-hexenal (BSA) Conjugate, MG-BSA, MG-BSA Conjugate, MG-modified BSA, 4-Hydroxy-2-hexenal-modified BSA, 4-Hydroxy-2-hexenal Bovine Serum Albumin Conjugate, 4-Hydroxy-2-hexenal-Bovine Serum Albumin Conjugate, 4-Hydroxy-2-hexenal (Bovine Serum Albumin) Conjugate, MG-Bovine Serum Albumin, MG-Bovine Serum Albumin Conjugate, MG-modified Bovine Serum Albumin, 4-Hydroxy-2-hexenal-modified Bovine Serum Albumin, 4-Hydroxy-2-hexenal-bovine serum albumin, 4-hydroxy Hexenal BSA Conjugate, HHE BSA Conjugate
UNSPSC
12352202
UN Code
Non-hazardous
Hazard Statement
Non-hazardous
Expression System
Synthetic
Host
Synthetic
Target
4-Hydroxy-2-hexenal BSA Conjugate
Conjugation
No tag
Applications
WB | ELISA
Field of Research
Cancer | Oxidative Stress | Lipid peroxidation
Purification Method
Filter Sterilized (0.2 µm)
Purification
Filter Sterilized (0.2 µm)
Limit Of Detection
Detectable in ELISA at ≥ 10 ng.
Concentration
Lot/batch specific. See included datasheet.
Purity
>98%
Weight
0.1
Buffer
PBS pH 7.4, 0.09% Sodium Azide
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For research use only.
Shipping Conditions
Blue Ice or 4ºC
Storage Conditions
-20ºC
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