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4-Hydroxy-2-hexenal BSA Conjugate

Bovine Serum Albumin (BSA) modified with 4-Hydroxy-2-hexenal (4-HHE)

Product Specifications

Background

4-Hydroxy-2-hexenal (HHE) BSA Conjugate is a lipid peroxidation marker used to study oxidative damage in neural tissues. HHE is generated from the oxidation of omega-3 polyunsaturated fatty acids and forms covalent adducts with proteins, altering their structure and function. In the nervous system, HHE accumulation is associated with mitochondrial dysfunction, synaptic impairment, and neuroinflammation. Elevated HHE levels have been observed in neurodegenerative conditions such as Alzheimer’s disease and ischemic brain injury, where they contribute to neuronal apoptosis and glial activation. The BSA-conjugated form allows for sensitive detection of HHE-modified proteins in immunoassays and histological studies. It supports research into the molecular mechanisms of oxidative stress and the development of antioxidant therapies targeting lipid peroxidation in neurodegeneration.

Product Name Alternative

4-Hydroxy-2-hexenal (4-HHE) BSA Conjugate, 4-Hydroxy-2-hexenal BSA Conjugate, 4-HHE BSA Conjugate, 4-Hydroxy-2-hexenal-BSA Conjugate, 4-Hydroxy-2-hexenal (BSA) Conjugate, MG-BSA, MG-BSA Conjugate, MG-modified BSA, 4-Hydroxy-2-hexenal-modified BSA, 4-Hydroxy-2-hexenal Bovine Serum Albumin Conjugate, 4-Hydroxy-2-hexenal-Bovine Serum Albumin Conjugate, 4-Hydroxy-2-hexenal (Bovine Serum Albumin) Conjugate, MG-Bovine Serum Albumin, MG-Bovine Serum Albumin Conjugate, MG-modified Bovine Serum Albumin, 4-Hydroxy-2-hexenal-modified Bovine Serum Albumin, 4-Hydroxy-2-hexenal-bovine serum albumin, 4-hydroxy Hexenal BSA Conjugate, HHE BSA Conjugate

UNSPSC

12352202

UN Code

Non-hazardous

Hazard Statement

Non-hazardous

Expression System

Synthetic

Host

Synthetic

Target

4-Hydroxy-2-hexenal BSA Conjugate

Conjugation

No tag

Applications

WB | ELISA

Field of Research

Cancer | Oxidative Stress | Lipid peroxidation

Purification Method

Filter Sterilized (0.2 µm)

Purification

Filter Sterilized (0.2 µm)

Limit Of Detection

Detectable in ELISA at ≥ 10 ng.

Concentration

Lot/batch specific. See included datasheet.

Purity

>98%

Weight

0.1

Buffer

PBS pH 7.4, 0.09% Sodium Azide

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For research use only.

Shipping Conditions

Blue Ice or 4ºC

Storage Conditions

-20ºC

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