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Tapinarof

Tapinarof (WBI-1001) is a natural aryl hydrocarbon receptor (AhR) agonist with an EC50 of 13 nM. Tapinarof resolves skin inflammation in mice[1].

Product Specifications

CAS Number

79338-84-4

Product Name Alternative

WBI-1001; Benvitimod; GSK2894512

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Aryl Hydrocarbon Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Tapinarof.html

Purity

99.95

Solubility

DMSO : 100 mg/mL (ultrasonic) |Ethanol : ≥ 100 mg/mL

Smiles

OC1=C(C(C)C)C(O)=CC(/C=C/C2=CC=CC=C2)=C1

Molecular Formula

C17H18O2

Molecular Weight

254.32

Precautions

H302, H315, H319, H335

References & Citations

[1]Smith SH, et al. Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans. J Invest Dermatol. 2017 Oct;137 (10) :2110-2119.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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