Tapinarof
Tapinarof (WBI-1001) is a natural aryl hydrocarbon receptor (AhR) agonist with an EC50 of 13 nM. Tapinarof resolves skin inflammation in mice[1].
Product Specifications
CAS Number
79338-84-4
Product Name Alternative
WBI-1001; Benvitimod; GSK2894512
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Aryl Hydrocarbon Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Tapinarof.html
Purity
99.95
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : ≥ 100 mg/mL
Smiles
OC1=C(C(C)C)C(O)=CC(/C=C/C2=CC=CC=C2)=C1
Molecular Formula
C17H18O2
Molecular Weight
254.32
Precautions
H302, H315, H319, H335
References & Citations
[1]Smith SH, et al. Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans. J Invest Dermatol. 2017 Oct;137 (10) :2110-2119.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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