SGN-2FF
SGN-2FF is a potent and orally active inhibitor of fucosylation, directly inhibits fucosyltransferase activity. SGN-2FF possesses antitumor activity[1].
Product Specifications
CAS Number
[2089647-47-0]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Glycosyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/SGN-2FF.html
Purity
98.0
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 36.67 mg/mL (ultrasonic)
Smiles
F[C@H]1[C@@H]([C@@H]([C@H](C)OC1O)O)O
Molecular Formula
C6H11FO4
Molecular Weight
166.15
Precautions
H315, H319, H320
References & Citations
[1]Stephen C. Alley, et al. Abstract DDT02-02: SGN-2FF: A novel small molecule inhibitor of fucosylation with preclinical antitumor activity through multiple immune mechanisms. Cancer Res 2017;77 (13 Suppl) .
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Curated Selection
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