CHK-336

CHK-336 (Example 1) is an orally active LDHA inhibitor (IC50[1].

Product Specifications

CAS Number

[2743436-86-2]

UNSPSC

12352005

Target

Lactate Dehydrogenase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/chk-336.html

Purity

98.50

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CSC(N2N=C(C(CC3=CC=C(S(=O)(N)=O)C(F)=C3)=C2CC4CC4)C5=CC=C(F)C=C5)=N1)O

Molecular Formula

C24H20F2N4O4S2

Molecular Weight

530.57

References & Citations

[1]David Andrew Powell, et al. Substituted pyrazolyl compounds and methods of use thereof. Patent WO2021234547A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Isoform

LDHA

Available Sizes

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