CHK-336
CHK-336 (Example 1) is an orally active LDHA inhibitor (IC50[1].
Product Specifications
CAS Number
[2743436-86-2]
UNSPSC
12352005
Target
Lactate Dehydrogenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/chk-336.html
Purity
98.50
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CSC(N2N=C(C(CC3=CC=C(S(=O)(N)=O)C(F)=C3)=C2CC4CC4)C5=CC=C(F)C=C5)=N1)O
Molecular Formula
C24H20F2N4O4S2
Molecular Weight
530.57
References & Citations
[1]David Andrew Powell, et al. Substituted pyrazolyl compounds and methods of use thereof. Patent WO2021234547A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
LDHA
Available Sizes
Curated Selection
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