Atorvastatin acetonide tert-butyl ester

Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids[1].

Product Specifications

CAS Number

[125971-95-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Intermediate

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/atorvastatin-acetonide-tert-butyl-ester.html

Purity

99.94

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(OC(C)(C)C)C[C@@H]1OC(C)(C)O[C@H](CCN2C(C3=CC=C(F)C=C3)=C(C4=CC=CC=C4)C(C(NC5=CC=CC=C5)=O)=C2C(C)C)C1

Molecular Formula

C40H47FN2O5

Molecular Weight

654.81

Precautions

H302, H315, H319, H335

References & Citations

[1]Process for preparing amorphous (4r-cis) -6-[2-[3-phenyl-4- (phenylcarbamoyl) -2- (4-fluorophenyl) -5- (1-methylethyl) -pyrrol-1-yl]-ethyl]-2,2-dimethyl-[1,3]-dioxane-4-yl-acetic acid. WO2005063741A1.