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Quercetin (GMP)

Quercetin GMP is Quercetin (HY-18085) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Quercetin is a flavonoid antioxidant, a PI3K inhibitor and a SIRT1 Activator[1][2][3][4][5][6].

Product Specifications

CAS Number

[117-39-5]

UNSPSC

12352005

Hazard Statement

H301

Target

Apoptosis; Autophagy; Mitophagy; PI3K; Reactive Oxygen Species (ROS)

Type

GMP Small Molecules

Related Pathways

Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/quercetin-gmp.html

Purity

99.7

Solubility

10 mM in DMSO

Smiles

OC1=C(C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C3C1=O

Molecular Formula

C15H10O7

Molecular Weight

302.24

Precautions

H301

References & Citations

[1]Zhou C, Lin Y. Osteogenic differentiation of adipose-derived stem cells promoted by quercetin. Cell Prolif. 2014 Apr;47 (2) :124-32.|[2]Wattel A, et al. Flavonoid quercetin decreases osteoclastic differentiation induced by RANKL via a mechanism involving NF kappa B and AP-1. J Cell Biochem. 2004 May 15;92 (2) :285-95.|[3]Zhou Y, et al. The Effect of Quercetin on the Osteogenesic Differentiation and Angiogenic Factor Expression of Bone Marrow-Derived Mesenchymal Stem Cells. PLoS One. 2015 Jun 8;10 (6) :e0129605.|[4]Woo JT, et al. Quercetin suppresses bone resorption by inhibiting the differentiation and activation of osteoclasts. Biol Pharm Bull. 2004 Apr;27 (4) :504-9.|[5]Kim YJ, et al. Quercetin, a flavonoid, inhibits proliferation and increases osteogenic differentiation in human adipose stromal cells. Biochem Pharmacol. 2006 Nov 15;72 (10) :1268-78.|[6]Pang XG, et al. Quercetin Stimulates Bone Marrow Mesenchymal Stem Cell Differentiation through an Estrogen Receptor-Mediated Pathway. Biomed Res Int. 2018 Mar 15;2018:4178021.

Shipping Conditions

Blue Ice

Storage Conditions

4°C, sealed storage, away from moisture and light

Scientific Category

GMP Small Molecules

Clinical Information

Phase 4

Citation 01

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