Quercetin (GMP)
Quercetin GMP is Quercetin (HY-18085) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Quercetin is a flavonoid antioxidant, a PI3K inhibitor and a SIRT1 Activator[1][2][3][4][5][6].
Product Specifications
CAS Number
[117-39-5]
UNSPSC
12352005
Hazard Statement
H301
Target
Apoptosis; Autophagy; Mitophagy; PI3K; Reactive Oxygen Species (ROS)
Type
GMP Small Molecules
Related Pathways
Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/quercetin-gmp.html
Purity
99.7
Solubility
10 mM in DMSO
Smiles
OC1=C(C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C3C1=O
Molecular Formula
C15H10O7
Molecular Weight
302.24
Precautions
H301
References & Citations
[1]Zhou C, Lin Y. Osteogenic differentiation of adipose-derived stem cells promoted by quercetin. Cell Prolif. 2014 Apr;47 (2) :124-32.|[2]Wattel A, et al. Flavonoid quercetin decreases osteoclastic differentiation induced by RANKL via a mechanism involving NF kappa B and AP-1. J Cell Biochem. 2004 May 15;92 (2) :285-95.|[3]Zhou Y, et al. The Effect of Quercetin on the Osteogenesic Differentiation and Angiogenic Factor Expression of Bone Marrow-Derived Mesenchymal Stem Cells. PLoS One. 2015 Jun 8;10 (6) :e0129605.|[4]Woo JT, et al. Quercetin suppresses bone resorption by inhibiting the differentiation and activation of osteoclasts. Biol Pharm Bull. 2004 Apr;27 (4) :504-9.|[5]Kim YJ, et al. Quercetin, a flavonoid, inhibits proliferation and increases osteogenic differentiation in human adipose stromal cells. Biochem Pharmacol. 2006 Nov 15;72 (10) :1268-78.|[6]Pang XG, et al. Quercetin Stimulates Bone Marrow Mesenchymal Stem Cell Differentiation through an Estrogen Receptor-Mediated Pathway. Biomed Res Int. 2018 Mar 15;2018:4178021.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from moisture and light
Scientific Category
GMP Small Molecules
Clinical Information
Phase 4
Citation 01
Mol Carcinog. 2024 Nov;63 (11) :2254-2268.|ACS Appl Mater Interfaces. 2025 Jan 22;17 (3) :4608-4625.|ACS Nano. 2025 Mar 25;19 (11) :11029-11048.|ACS Omega. 2025 Apr 29;10 (18) :19019-19032.|Adv Funct Mater. 27 January 2022.|Aging (Albany NY) . 2021 Nov 25;13 (22) :24753-24767.|Aging. 2020 Jun 25;12 (12) :11337-11348.|Am J Chin Med. 2025 Aug 30:1-32.|Antioxidants (Basel) . 2022 Feb 14;11 (2) :385.|Antioxidants (Basel) . 2022 Nov 11;11 (11) :2222.|Antioxidants (Basel) . 2024 Jul 29;13 (8) :918.|APL Bioeng. 2025 Jul 24;9 (3) :036108.|Autophagy. 2025 May 31:1-21.|Behav Brain Res. 2023 Feb 25:440:114260.|Biochem Syst Ecol. 2025 Oct.|Biol Pharm Bull. 2025;48 (10) :1514-1525.|Biol Proced Online. 2025 Jun 16;27 (1) :21.|Biology (Basel) . 2024 Aug 29;13 (9) :676.|Biomed Pharmacother. 2024 Jun:175:116606.|Biomed Res Int. 2022 Jul 23:2022:8080679.|Bioresour Bioprocess. 2024 Nov 27;11 (1) :108.|bioRxiv. 2023 Dec 20.|bioRxiv. 2024 Jul 30:2024.07.29.605645.|bioRxiv. 2025 Feb 6:2025.02.06.636893.|bioRxiv. 2025 Jun 27.|BMC Complement Med Ther. 2023 Dec 1;23 (1) :433.|BMC Complement Med Ther. 2023 Mar 23;23 (1) :89.|Breast Cancer. 2024 Dec 20:16:993-1004.|Cancer Rep (Hoboken) . 2025 May;8 (5) :e70169.|Cancer Rep (Hoboken) . 2025 May;8 (5) :e70220.|Cell Biochem Biophys. 2025 Feb 18.|Cell Metab. 2025 Oct 24:S1550-4131 (25) 00395-X.|Cell Mol Gastroenterol Hepatol. 2022 Apr 2;14 (1) :75-99.|Cell Stem Cell. 2025 Dec 4;32 (12) :1869-1885.e8.|Chem Biol Drug Des. 2024 Apr;103 (4) :e14520.|Chem Biol Interact. 2024 May 19:396:111064.|Chemistry of Plant Raw Material. 2025.|Chin J Integr Med. 2023 Mar;29 (3) :205-212.|Chin J Integr Med. 2025 Jun 24.|Chin Med. 2024 Mar 18;19 (1) :48.|Clin Exp Ophthalmol. 2025 Jul 14.|Comput Struct Biotechnol J. 2021 Oct 1:19:5568-5577.|Cryobiology. 2025 Sep:120:105299.|Diabetes Metab Syndr Obes. 2025 Aug 5:18:2681-2694.|Drug Des Devel Ther. 2025 Jun 20:19:5293-5310.|Ecotoxicol Environ Saf. 2024 Oct 15:285:117136.|Environ Pollut. 2021 Dec 1:290:118036.|Eur J Med Chem. 2018 Mar 25:148:63-72.|Eur J Med Res. 2022 Dec 15;27 (1) :292.|Eur J Pharmacol. 2025 Dec 5:1008:178309.|Evid Based Complement Alternat Med. 2021 Aug 26:2021:7169211.|Evid Based Complement Alternat Med. 2022 May 9;2022:2256671.|Exp Cell Res. 2020 Aug 1;393 (1) :112054.|Exp Eye Res. 2022 Oct:223:109207.|Exp Eye Res. 2023 Apr:229:109416.|Exp Ther Med. 2021 May;21 (5) :468.|Food Chem Toxicol. 2024 Jul 23:114877.|Food Chem. 2023 Mar 30;405 (Pt A) :134807.|Food Chem. 2025 Dec 30:497:146992.|Food Chem. 2025 May 31:489:144992.|Food Res Int. 2025 Sep 26;222:117620.|Food Sci Nutr. 2025 Aug 4;13 (8) :e70757.|Free Radic Biol Med. 2024 Mar:213:150-163.|Free Radic Biol Med. 2025 Oct 1:241:543-555.|Front Biosci (Landmark Ed) . 2025 Jul 25;30 (7) :40077.|Front Cardiovasc Med. 2022 Jun 16:9:804801.|Front Immunol. 2025 Mar 17:16:1532336.|Front Oncol. 2022 Aug 10;12:882784.|Genomics. 2021 Jul;113 (4) :2702-2716.|Gerontology. 2022;68 (8) :920-934.|Heliyon. 2024 Aug 2;10 (16) :e35489.|Heliyon. 2024 Sep 20;10 (19) :e38122.|Immunobiology. 2022 Dec 30;228 (2) :152324.|Immunobiology. 2023 Mar;228 (2) :152324.|Infect Drug Resist. 2025 Jul 3:18:3257-3277.|Inflamm Res. 2020 Dec;69 (12) :1201-1213.|Inflammopharmacology. 2025 Feb;33 (2) :865-883.|Inflammopharmacology. 2025 Mar;33 (3) :1435-1454.|Insects. 2018 Jun 29;9 (3) . pii: E77. |Int Immunopharmacol. 2024 Nov 2;143 (Pt 3) :113546.|Int Immunopharmacol. 2024 Sep 27;142 (Pt B) :113162.|Int Immunopharmacol. 2025 Mar 29:154:114559.|Int J Biol Macromol. 2025 Jan 5:139468.|Int J Biol Sci. 2025 Jan 6;21 (3) :940-954.|Int J Insect Sci. 2018 Feb 28:10:1179543318758409.|Int J Mol Med. 2023 Dec;52 (6) :116.|Int J Mol Med. 2025 Jan;55 (1) :4.|Int J Mol Sci. 2024 Apr 4;25 (7) :4031.|Int J Mol Sci. 2024 Jul 7;25 (13) :7461.|Int J Nanomedicine. 2025 Aug 25:20:10255-10277.|International Journal of Human Anatomy. 2020 Dec.|Invest Ophthalmol Vis Sci. 2024 Nov 4;65 (13) :11.|J Agric Food Chem. 2020 Jul 29;68 (30) :8050-8056.|J Agric Food Chem. 2023 May 17;71 (19) :7427-7439.|J Agric Food Chem. 2024 Mar 27;72 (12) :6651-6659.|J Agric Food Chem. 2025 Jul 9;73 (27) :16787-16803.|J Anim Sci Biotechnol. 2024 Dec 8;15 (1) :168.|J Anim Sci Biotechnol. 2024 Sep 5;15 (1) :119.|J Biochem Mol Toxicol. 2025 Sep;39 (9) :e70463.|J Biomed Sci. 2025 Feb 5;32 (1) :15.|J Control Release. 2025 Jun 10:382:113642.|J Crohns Colitis. 2025 Jul 29.|J Environ Sci. 2025 Sep 20.|J Ethnopharmacol. 2024 Jul 11:118576.|J Food Biochem. 2024 Aug 28.|J Funct Foods. 2024 Aug.|J Hazard Mater Lett. 2025 Nov.|J Herb Med. 2025 Aug 20.|J Inflamm Res. 2021 Dec 7;14:6601-6618.|J Mol Liq. 23 November 2021, 118164.|J Periodontal Res. 2023 Oct;58 (5) :1082-1095.|J Tradit Chinese Medical Sci. 2024 Jun 12.|JCI Insight. 2025 Jan 23;10 (2) :e180248.|Life Sci. 2020 Sep 15;257:118116.|Mater Today Bio. 2024 Dec 28:30:101432.|Mater Today Bio. 2025 May 28:32:101896. |Medicine. 2023 Oct 13;102 (41) :e35384.|Mol Cancer Ther. 2025 Jul 2.|Mol Divers. 2025 Jan 16.|Mol Med Rep. 2024 Feb;29 (2) :26.|Mol Med Rep. 2025 Mar;31 (3) :60.|Mol Med Rep. 2026 Jan;33 (1) :7.|Mol Nutr Food Res. 2025 Jun 16:e70144.|Molecules. 2020 Apr 23;25 (8) :1980.|Molecules. 2023 Mar 23;28 (7) :2903.|Nat Aging. 2024 Apr;4 (4) :527-545.|Nat Commun. 2025 Jan 6;16 (1) :424.|Naunyn Schmiedebergs Arch Pharmacol. 2023 Nov;396 (11) :3045-3059.|Naunyn Schmiedebergs Arch Pharmacol. 2024 Nov;397 (11) :9095-9110.|Naunyn Schmiedebergs Arch Pharmacol. 2024 Sep;397 (9) :6837-6850.|Naunyn Schmiedebergs Arch Pharmacol. 2025 Jan;398 (1) :951-965.|Naunyn Schmiedebergs Arch Pharmacol. 2025 Nov 20.|Osteoarthritis Cartilage. 2021 Mar;29 (3) :413-422.|Oxid Med Cell Longev. 2022 Sep 5:2022:7769355.|Pestic Biochem Physiol. 2025 Dec.|Pharmaceutics. 2025 Mar 26;17 (4) :423.|Pharmacological Research-Modern Chinese Medicine. 2024 Mar, 10, 100360.|Phytomedicine. 2025 May 27:143:156911.|Phytomedicine. 2025 May:140:156484.|Phytomedicine. 2025 May:140:156573.|Phytomedicine. 2025 Oct 3:148:157357.|Phytomedicine. 2025 Sep 23.|Plant Foods Hum Nutr. 2022 Dec;77 (4) :529-537.|Plant Methods. 2022 Jun 23;18 (1) :87.|PLoS One. 2024 Jul 11;19 (7) :e0305612.|Redox Biol. 2025 Aug 8:86:103816.|Regulatory Research and Medicine Evaluation. 2025.|Res Sq. 2025 Jul 17.|Res Sq. 2025 Nov 12.|Research Square Preprint. 2021. Jul.|Research Square Preprint. 2024 Dec 13.|Research Square Print. 2025 May 28.|Respir Res. 2024 Aug 2;25 (1) :294.|Rheumatology (Oxford) . 2025 Aug 13:keaf437.|Sci Rep. 2024 Jun 20;14 (1) :14183.|Sci Rep. 2025 Aug 19;15 (1) :28604.|Sci Rep. 2025 Jan 20;15 (1) :2490.|Sci Rep. 2025 Nov 21;15 (1) :41324.|SSRN. 2025 Jul 8.|SSRN. 2025 May 7.|Thorac Cancer. 2021 May;12 (9) :1415-1422.|Tissue Eng Regen Med. 2024 Oct;21 (7) :1061-1077.|Toxicol In Vitro. 2025 Dec:109:106128.|Toxicon. 2025 Oct:265:108477.|Virus Res. 2021 Nov:305:198556.|World J Stem Cells. 2023 Aug 26;15 (8) :842-865.|J Biomed Mater Res A. 2025 Oct;113 (10) :e37999.|J Nanobiotechnology. 2025 Jul 22;23 (1) :536.|Phytomedicine. 2025 Nov 22:150:157586.
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
