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WNK1 Antibody (pSer382)

Rabbit Anti-Human WNK1 (pSer382) Polyclonal

Product Specifications

Background

WINK1 is a serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signalling, survival, and proliferation.WNK1 activates SCNN1A, SCNN1B, SCNN1D and SGK1. Exact mechanism of oncogenesis is unclear.

Specifications

Detects 250.756 kDa.

Product Name Alternative

Cell Signaling, Protein Phosphorylation, Serine / Threonine Kinases

Gene ID

65125

Swiss Prot

Q9H4A3

Accession Number

NP_061852

Cellular Locus

Cytoplasm

Host

Rabbit

Species Reactivity

Human

Immunogen

A phospho-specific peptide corresponding to residues surrounding Ser382 of human WNK1 (AA379-385)

Target

WNK1 (pSer382)

Clonality

Polyclonal

Conjugation

Unconjugated

Tissue Specificity

Highly expressed in the testis, heart, kidney and skeletal muscle. Isoform 3 is kidney-specific and specifically expressed in the distal convoluted tubule (DCT) and connecting tubule (CNT) of the nephron.

Validated Applications

WB,AM

Purification

Peptide Affinity Purified

Dilution

WB (1:250); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer changes when conjugated

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Product MSDS

https://cdn.gentaur.com/products/400/4423137/msds/spc-1097d.pdf

CAS Number

9007-83-4

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