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NDR1 Antibody (pSer281+pThr282): Biotin

Rabbit Anti-Human NDR1 (pSer281+pThr282) Polyclonal

Product Specifications

Background

STK38 is a negative regulator of MAP3K1/2 signalling. Converts MAP3K2 from its phosphorylated form to its nonphosphorylated form and inhibits autophosphorylation of MAP3K2. The MAPK/ERK pathway has been implicated in oncogenesis as either a promoter or inhibitor depending on the cancer system. Thus, the role of STK38 in cancer is likely highly contextual.

Specifications

Detects 54.19 kDa.

Product Name Alternative

Neuroscience, Neurodegeneration, Cancer, Tumor Biomarkers, Oncoproteins, Signal Transducers, Cardiovascular System, Angiogenesis

Gene ID

11329

Swiss Prot

Q15208

Accession Number

NP_009202

Cellular Locus

Nucleus | Cytoplasm

Host

Rabbit

Species Reactivity

Human

Immunogen

A phospho-specific peptide corresponding to residues surrounding Ser281 and Thr282 of human NDR1 (AA278-285)

Target

NDR1 (pSer281+pThr282)

Clonality

Polyclonal

Conjugation

Biotin

Tissue Specificity

Ubiquitously expressed with highest levels observed in peripheral blood leukocytes.

Validated Applications

WB,IHC,ICC/IF |ELISA

Purification

Peptide Affinity Purified

Dilution

WB (1:250); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

136.36mM Ethanolamine, and 9.55mM Sodium Bicarbonate in 95.45% PBS

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Product Datasheet

https://cdn.gentaur.com/products/400/4421661/datasheet/spc-1035d-bi.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4421661/msds/spc-1035d-bi.pdf

CAS Number

9007-83-4

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