CDK7 ligand 1

CDK7 ligand 1 is an active control ligand for CDK7 ligand 2 (HY-161830) . CDK7 ligand 2 is a CDK7 ligand. CDK7 ligand 2 can be used in the synthesis of PROTACs[1].

Product Specifications

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdk7-ligand-1.html

Smiles

O=C(NC1=NNC2=C1CN(C(N[C@@H](C3=CC=CC=C3)CN(C)C)=O)C2(C)C)C4=CC=C(I)C=C4

Molecular Formula

C25H29IN6O2

Molecular Weight

572.44

References & Citations

[1]Wenzhi Ji, et al. Discovery of Bivalent Small Molecule Degraders of Cyclin-dependent Kinase 7 (CDK7) . European Journal of Medicinal Chemistry (2024) : 116613.