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CDK7 ligand 1

Product Specifications

UNSPSC Description

CDK7 ligand 1 is an active control ligand for CDK7 ligand 2 (HY-161830). CDK7 ligand 2 is a CDK7 ligand. CDK7 ligand 2 can be used in the synthesis of PROTACs[1].

Target Antigen

Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdk7-ligand-1.html

Smiles

O=C(NC1=NNC2=C1CN(C(N[C@@H](C3=CC=CC=C3)CN(C)C)=O)C2(C)C)C4=CC=C(I)C=C4

Molecular Weight

572.44

References & Citations

[1]Wenzhi Ji, et al. Discovery of Bivalent Small Molecule Degraders of Cyclin-dependent Kinase 7 (CDK7). European Journal of Medicinal Chemistry (2024): 116613.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-161829/CDK7-ligand-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-161829/

Clinical Information

No Development Reported

Curated Selection

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