G6PD Antibody (pTyr401)
Rabbit Anti-Human G6PD (pTyr401) Polyclonal
Product Specifications
Background
Glucose-6-phosphate 1-dehydrogenase (G6PD) plays an important role in the pentose phosphate pathway. It is a member of the glucose-6-phosphate dehydrogenase family of proteins. G6PD is an ubiquitous enzyme that produces pentose sugars for nucleic acid synthesis, but is also involved in carbohydrate degradation, as it is one of the main producers of NADPH reducing power. G6PD has NADP as a co-factor and structural element. It can be found as a homodimer or homotetramer, and is primarily detected in lymphoblasts, granulocytes and sperm. Defects in G6PD can cause chronic non-spherocytic hemolytic anemia (CNSHA), especially in areas in which malaria is an epidemic. Individuals with a high level of G6PD-deficiency are at higher risk of acute hemolytic attacks.
Specifications
Detects 59.257 kDa.
Product Name Alternative
Cardiovascular System, Atherosclerosis, Diabetes Associated, Cardiovascular System, Heart, Cardiac Metabolism, Cancer, Cancer Metabolism, Cancer Carbohydrate Metabolism, Cell Signaling, Metabolism, Diabetes
Gene ID
2539
Swiss Prot
P11413
Accession Number
NP_000393
Cellular Locus
Cytoplasm | Cytosol | Extracellular Endosome | Membrane | Nucleus
Host
Rabbit
Species Reactivity
Human
Immunogen
A phospho-specific peptide corresponding to residues surrounding Tyr401 of human G6PD (AA398-404)
Target
G6PD (pTyr401)
Clonality
Polyclonal
Conjugation
Unconjugated
Validated Applications
WB,AM
Purification
Peptide Affinity Purified
Dilution
WB (1:250); optimal dilutions for assays should be determined by the user.
Weight
0.1
Buffer
PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer changes when conjugated
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Product MSDS
https://cdn.gentaur.com/products/400/4420473/msds/spc-986d.pdf
CAS Number
9007-83-4
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