ND-378

ND-378 is a potent and selective inhibitor of matrix metalloproteinases (MMP-2) with a Ki value of 230 nM. ND-378 can be used to study spinal cord injury (SCI) [1].

Product Specifications

CAS Number

[1807453-72-0]

UNSPSC

12352005

Target

MMP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nd-378.html

Smiles

O=C(C)NCC1=CC=C(C=C1)OC2=CC=C(S(=O)(CC3SC3)=O)C=C2

Molecular Formula

C18H19NO4S2

Molecular Weight

377.48

References & Citations

[1]Gao M, et al. Selective Inhibition of MMP-2 Does Not Alter Neurological Recovery after Spinal Cord Injury. ACS Chem Neurosci. 2016 Nov 16;7 (11) :1482-1487.