ND-378
ND-378 is a potent and selective inhibitor of matrix metalloproteinases (MMP-2) with a Ki value of 230 nM. ND-378 can be used to study spinal cord injury (SCI) [1].
Product Specifications
CAS Number
1807453-72-0
UNSPSC
12352005
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nd-378.html
Smiles
O=C(C)NCC1=CC=C(C=C1)OC2=CC=C(S(=O)(CC3SC3)=O)C=C2
Molecular Formula
C18H19NO4S2
Molecular Weight
377.48
References & Citations
[1]Gao M, et al. Selective Inhibition of MMP-2 Does Not Alter Neurological Recovery after Spinal Cord Injury. ACS Chem Neurosci. 2016 Nov 16;7 (11) :1482-1487.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RK11791 96 Tests
Human Proteasome subunit beta type-6 (PSMB6) ELISA Kit
Sign In for Pricing
View Details HY-168401 1 Each
3',4'-Trimethylene-α-ethylaminovalerophenone (hydrochloride)
Sign In for Pricing
View Details 
243319 100 µL
AMY2A (Amylase, alpha 2A (Pancreatic), AMY2, AMY2B, PA)
Sign In for Pricing
View Details