ND-378
ND-378 is a potent and selective inhibitor of matrix metalloproteinases (MMP-2) with a Ki value of 230 nM. ND-378 can be used to study spinal cord injury (SCI) [1].
Product Specifications
CAS Number
[1807453-72-0]
UNSPSC
12352005
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nd-378.html
Smiles
O=C(C)NCC1=CC=C(C=C1)OC2=CC=C(S(=O)(CC3SC3)=O)C=C2
Molecular Formula
C18H19NO4S2
Molecular Weight
377.48
References & Citations
[1]Gao M, et al. Selective Inhibition of MMP-2 Does Not Alter Neurological Recovery after Spinal Cord Injury. ACS Chem Neurosci. 2016 Nov 16;7 (11) :1482-1487.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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