TTK ligand 2
TTK ligand 2 is a monopolar spindle 1 (TTK) ligand that can be used in the synthesis of PROTACT (HY-168540) [1].
Product Specifications
UNSPSC
12352211
Target
Ligands for Target Protein for PROTAC; Mps1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ttk-ligand-2.html
Purity
98.96
Smiles
N1(C2=CC=C(NC3=NC(NC4CCCCC4)=C5N=CNC5=N3)C=C2)CCNCC1
Molecular Formula
C21H28N8
Molecular Weight
392.50
References & Citations
[1]Sflakidou E, et, al. Development of 2-Aminoadenine-Based Proteolysis-Targeting Chimeras (PROTACs) as Novel Potent Degraders of Monopolar Spindle 1 and Aurora Kinases. ACS Pharmacol. Transl. Sci. 2024.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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