TTK ligand 2

TTK ligand 2 is a monopolar spindle 1 (TTK) ligand that can be used in the synthesis of PROTACT (HY-168540) [1].

Product Specifications

UNSPSC

12352211

Target

Ligands for Target Protein for PROTAC; Mps1

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ttk-ligand-2.html

Purity

98.96

Smiles

N1(C2=CC=C(NC3=NC(NC4CCCCC4)=C5N=CNC5=N3)C=C2)CCNCC1

Molecular Formula

C21H28N8

Molecular Weight

392.50

References & Citations

[1]Sflakidou E, et, al. Development of 2-Aminoadenine-Based Proteolysis-Targeting Chimeras (PROTACs) as Novel Potent Degraders of Monopolar Spindle 1 and Aurora Kinases. ACS Pharmacol. Transl. Sci. 2024.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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