Pseudothymidine

Pseudothymidine is a C-nucleoside analog of thymidine.

Product Specifications

CAS Number

[65358-15-8]

Product Name Alternative

5-Methyl-2'-Deoxypseudouridin

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HIV; Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Pseudothymidine.html

Purity

99.44

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C(NC1=O)N(C)C=C1[C@H]2C[C@H](O)[C@@H](CO)O2

Molecular Formula

C10H14N2O5

Molecular Weight

242.23

Precautions

H302, H315, H319, H335

References & Citations

[1]S Lutz, et al. An in vitro screening technique for DNA polymerases that can incorporate modified nucleotides. Pseudo-thymidine as a substrate for thermostable polymerases. Nucleic Acids Res. 1999 Jul 1; 27 (13) : 2792-2798.|[2]Havemann SA, et al. Incorporation of multiple sequential pseudothymidines by DNA polymerases and their impact on DNA duplex structure. Nucleosides Nucleotides Nucleic Acids. 2008 Mar;27 (3) :261-78.