Human ARL3 Protein

<strong>Human ARL3 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011771_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1.0 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> ARL 3 protein, ADP-ribosylation factor-like protein 3 protein, ARFL3 protein, ARL3, ARL-3 protein, ARL-3, ARL 3_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Fahim AT, Daiger SP, Weleber RG. Nonsyndromic Retinitis Pigmentosa Overview 2000 Aug 4 [updated 2017 Jan 19]. In: Adam MP, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews(®) [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2022._x000D_ 2: Hanke-Gogokhia C, Wu Z, Gerstner CD, Frederick JM, Zhang H, Baehr W. Arf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors J Biol Chem. 2016 Mar 25;291(13):7142-55._x000D_ 3: Alkanderi S, Molinari E, Shaheen R, Elmaghloob Y, Stephen LA, Sammut V, Ramsbottom SA, Srivastava S, Cairns G, Edwards N, Rice SJ, Ewida N, Alhashem A, White K, Miles CG, Steel DH, Alkuraya FS, Ismail S, Sayer JA. ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein Composition Am J Hum Genet. 2018 Oct 4;103(4):612-620._x000D_ 4: ElMaghloob Y, Sot B, McIlwraith MJ, Garcia E, Yelland T, Ismail S. ARL3 activation requires the co-GEF BART and effector-mediated turnover Elife. 2021 Jan 13;10:e64624._x000D_ 5: Grayson C, Bartolini F, Chapple JP, Willison KR, Bhamidipati A, Lewis SA, Luthert PJ, Hardcastle AJ, Cowan NJ, Cheetham ME. Localization in the human retina of the X-linked retinitis pigmentosa protein RP2, its homologue cofactor C and the RP2 interacting protein Arl3 Hum Mol Genet. 2002 Nov 15;11(24):3065-74._x000D_ 6: Hanke-Gogokhia C, Frederick JM, Zhang H, Baehr W. Binary Function of ARL3-GTP Revealed by Gene Knockouts Adv Exp Med Biol. 2018;1074:317-325._x000D_ 7: Kühnel K, Veltel S, Schlichting I, Wittinghofer A. Crystal structure of the human retinitis pigmentosa 2 protein and its interaction with Arl3 Structure. 2006 Feb;14(2):367-78._x000D_ 8: Schwarz N, Hardcastle AJ, Cheetham ME. Arl3 and RP2 mediated assembly and traffic of membrane associated cilia proteins Vision Res. 2012 Dec 15;75:2-4._x000D_ 9: Holtan JP, Teigen K, Aukrust I, Bragadóttir R, Houge G. Dominant ARL3-related retinitis pigmentosa Ophthalmic Genet. 2019 Apr;40(2):124-128._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/26551564">10: Gotthardt K, Lokaj M, Koerner C, Falk N, Gießl A, Wittinghofer A. A G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins Elife. 2015 Nov 9;4:e11859. </a>_x000D_ _x000D_ <strong>Products Related to Human ARL3 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>