Hedgehog IN-1
Hedgehog IN-1 (Compound 7d) is an inhibitor for Hedgehog protein with IC50 of 70 nM[1].
Product Specifications
CAS Number
[330796-24-2]
UNSPSC
12352005
Target
Hedgehog
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease; Others
Assay Protocol
https://www.medchemexpress.com/hedgehog-in-1.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
O=C(NCC1=NC2=C(C(N1C3=CC=C(C=C3)F)=O)C=CC=C2)NC4=CC=C(C(C(F)(F)F)=C4)Cl
Molecular Formula
C23H15ClF4N4O2
Molecular Weight
490.84
References & Citations
[1]Brunton SA, et al., Potent inhibitors of the hedgehog signaling pathway. J Med Chem. 2008 Mar 13;51 (5) :1108-10.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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