Hedgehog IN-1

Hedgehog IN-1 (Compound 7d) is an inhibitor for Hedgehog protein with IC50 of 70 nM[1].

Product Specifications

CAS Number

[330796-24-2]

UNSPSC

12352005

Target

Hedgehog

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease; Others

Assay Protocol

https://www.medchemexpress.com/hedgehog-in-1.html

Purity

99.0

Solubility

10 mM in DMSO

Smiles

O=C(NCC1=NC2=C(C(N1C3=CC=C(C=C3)F)=O)C=CC=C2)NC4=CC=C(C(C(F)(F)F)=C4)Cl

Molecular Formula

C23H15ClF4N4O2

Molecular Weight

490.84

References & Citations

[1]Brunton SA, et al., Potent inhibitors of the hedgehog signaling pathway. J Med Chem. 2008 Mar 13;51 (5) :1108-10.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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