WAY-169916
WAY-169916 is a pathway-selective ligand of ER (estrogen receptor) that acts by inhibiting NF-kB transcriptional activity. WAY-169916 has potent anti-inflammatory effect[1].
Product Specifications
CAS Number
669764-18-5
UNSPSC
12352005
Target
Estrogen Receptor/ERR; NF-κB
Type
Reference compound
Related Pathways
NF-κB; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/way-169916.html
Purity
99.32
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C(O)=C1)C2=NN(C3=C2C=CC=C3C(F)(F)F)CC=C
Molecular Formula
C17H13F3N2O2
Molecular Weight
334.29
References & Citations
[1]Chadwick CC, et al. Identification of pathway-selective estrogen receptor ligands that inhibit NF-kappaB transcriptional activity. Proc Natl Acad Sci U S A. 2005 Feb 15;102 (7) :2543-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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