WAY-169916
WAY-169916 is a pathway-selective ligand of ER (estrogen receptor) that acts by inhibiting NF-kB transcriptional activity. WAY-169916 has potent anti-inflammatory effect[1].
Product Specifications
CAS Number
669764-18-5
UNSPSC
12352005
Target
Estrogen Receptor/ERR; NF-κB
Type
Reference compound
Related Pathways
NF-κB; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/way-169916.html
Purity
99.32
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C(O)=C1)C2=NN(C3=C2C=CC=C3C(F)(F)F)CC=C
Molecular Formula
C17H13F3N2O2
Molecular Weight
334.29
References & Citations
[1]Chadwick CC, et al. Identification of pathway-selective estrogen receptor ligands that inhibit NF-kappaB transcriptional activity. Proc Natl Acad Sci U S A. 2005 Feb 15;102 (7) :2543-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC421828 20 µg
TXNRD3IT1 (TXNRD3NB) (NM_001039783) Human Over-expression Lysate
Sign In for Pricing
View Details