TX2-120-1
TX2-120-1 possesses the ability to bind to Her3, with an IC50 value of 56 nM for Her3. TX2-120-1 can be used for the synthesis of TX2-121-1 (HY-118998) [1].
Product Specifications
CAS Number
[1603845-45-9]
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tx2-120-1.html
Smiles
CN1CCC(N2C3=NC=NC(N)=C3C(C(C=C4)=CC(NC(C=C)=O)=C4OC5=CC=CC=C5)=N2)CC1
Molecular Formula
C26H27N7O2
Molecular Weight
469.54
References & Citations
[1]Lim S M, et al. Development of small molecules targeting the pseudokinase Her3[J]. Bioorganic & medicinal chemistry letters, 2015, 25 (16) : 3382-3389.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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