TX2-120-1

TX2-120-1 possesses the ability to bind to Her3, with an IC50 value of 56 nM for Her3. TX2-120-1 can be used for the synthesis of TX2-121-1 (HY-118998) [1].

Product Specifications

CAS Number

[1603845-45-9]

UNSPSC

12352005

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tx2-120-1.html

Smiles

CN1CCC(N2C3=NC=NC(N)=C3C(C(C=C4)=CC(NC(C=C)=O)=C4OC5=CC=CC=C5)=N2)CC1

Molecular Formula

C26H27N7O2

Molecular Weight

469.54

References & Citations

[1]Lim S M, et al. Development of small molecules targeting the pseudokinase Her3[J]. Bioorganic & medicinal chemistry letters, 2015, 25 (16) : 3382-3389.