Cholesterol myristate

Cholesterol myristate is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels such as the nicotinic acetylcholine receptor, GABAA receptor, and the inward-rectifier potassium ion channel.

Product Specifications

CAS Number

[1989-52-2]

Product Name Alternative

Cholesteryl myristate; Cholesteryl tetradecanoate

UNSPSC

12352211

Hazard Statement

H302

Target

Endogenous Metabolite; GABA Receptor; nAChR; Potassium Channel

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Cholesterol_myristate.html

Purity

98.0

Solubility

Ethanol : 3.33 mg/mL (ultrasonic)

Smiles

C[C@@]12[C@]3([H])[C@](CC=C1C[C@@H](OC(CCCCCCCCCCCCC)=O)CC2)([H])[C@@]4([H])[C@@](C)([C@]([C@H](C)CCCC(C)C)([H])CC4)CC3

Molecular Formula

C41H72O2

Molecular Weight

597.01

Precautions

P264-P270-P330-P501

References & Citations

[1]Chen DF, et al. Cholesterol myristate suppresses the apoptosis of mesenchymal stem cells via upregulation of inhibitor of differentiation. Steroids. 2010 Dec 12;75 (13-14) :1119-26.|[2]Chen DF, et al. BMP-Id pathway targeted by cholesterol myristate suppresses the apoptosis of PC12 cells. Brain Res. 2011 Jan 7;1367:33-42.|[3]Levitan I, et al. Cholesterol binding to ion channels. Front Physiol. 2014 Feb 26;5:65.