GGFG-PAB-Exatecan (TFA)
GGFG-PAB-Exatecan TFA consists of an ADC toxin Exatecan (HY-13631) and a linker GGFG-PAB, and can be used as a drug-linker conjugate for the synthesis of ADC molecules[1].
Product Specifications
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ggfg-pab-exatecan-tfa.html
Smiles
NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(NC(C=C2)=CC=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C49H48F4N8O12
Molecular Weight
1016.95
References & Citations
[1]Zhang F, et al., Epsilon-poly-l-lysine-based drug conjugate, intermediate thereof, and application thereof. WO2023078464.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Rabbit Monoclonal Serpin G1/C1 Inhibitor Antibody (018) [Janelia Fluor 646]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
NBP2-89738JF646 0.1 mL
Rabbit Monoclonal Serpin G1/C1 Inhibitor Antibody (018) [Janelia Fluor 646]
Sign In for Pricing
View Details 
K6222406 1.0 µg DNA
Slc12a6 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)
Sign In for Pricing
View Details 584779-01 20 µg
Heat Shock 70kD Protein, Recombinant, Chicken, aa3-389, His-Tag
Sign In for Pricing
View Details 584779-02 100 µg
Heat Shock 70kD Protein, Recombinant, Chicken, aa3-389, His-Tag
Sign In for Pricing
View Details