GGFG-PAB-Exatecan (TFA)
GGFG-PAB-Exatecan TFA consists of an ADC toxin Exatecan (HY-13631) and a linker GGFG-PAB, and can be used as a drug-linker conjugate for the synthesis of ADC molecules[1].
Product Specifications
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ggfg-pab-exatecan-tfa.html
Smiles
NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(NC(C=C2)=CC=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C49H48F4N8O12
Molecular Weight
1016.95
References & Citations
[1]Zhang F, et al., Epsilon-poly-l-lysine-based drug conjugate, intermediate thereof, and application thereof. WO2023078464.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
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