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GGFG-PAB-Exatecan (TFA)

Product Specifications

UNSPSC Description

GGFG-PAB-Exatecan TFA consists of an ADC toxin Exatecan (HY-13631) and a linker GGFG-PAB, and can be used as a drug-linker conjugate for the synthesis of ADC molecules[1].

Target Antigen

Drug-Linker Conjugates for ADC; Topoisomerase

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ggfg-pab-exatecan-tfa.html

Smiles

NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(NC(C=C2)=CC=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O

Molecular Weight

1016.95

References & Citations

[1]Zhang F, et al., Epsilon-poly-l-lysine-based drug conjugate, intermediate thereof, and application thereof. WO2023078464.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-153069A/GGFG-PAB-Exatecan-TFA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-153069A/

Clinical Information

No Development Reported

Curated Selection

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