WDR45 Antibody
Rabbit Anti-Human WDR45 Polyclonal
Product Specifications
Background
WIPI-4 is a 360 amino acid protein containing three WD repeats. Existing as three alternatively spliced isoforms, WIPI-4 is ubiquitously expressed but found at highest levels in heart and skeletal muscle. WD repeat proteins are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Diseases associated with this gene include neurodegeneration with brain iron accululation 5 and 4.
Specifications
Detects ~40 kDa.
Product Name Alternative
Cancer, Autophagy, Cell Signaling, Apoptosis
UNSPSC
12352203
Gene ID
11152
Swiss Prot
Q9Y484
Accession Number
NP_001025067.1
Cellular Locus
0
Host
Rabbit
Species Reactivity
Human,Rat
Immunogen
Synthetic peptide from the C-terminal of Human WIPI4 (aa. 312-322)
Target
WDR45
Clonality
Polyclonal
Conjugation
Unconjugated
Tissue Specificity
Ubiquitously expressed, with high expression in skeletal muscle and heart. Weakly expressed in liver and placenta. Expression is down-regulated in pancreatic and in kidney tumors.
Validated Applications
WB,ICC/IF
Purification
Peptide Affinity Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Weight
0.012
Buffer
PBS, 50% glycerol, 0.09% sodium azide *Storage buffer changes when conjugated
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. http://www.genecards.org/cgi-bin/carddisp.pl?gene=WDR45 2. Strausberg R.L., et al. (2002) Proc Natl Acad Sci U S A. 99(26): 16899–16903.
3. Haack T.B., et al. (2012) Am J Hum Genet. 91(6): 1144–1149.
Product MSDS
https://cdn.gentaur.com/products/400/4415308/msds/spc-651s.pdf
CAS Number
9007-83-4
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