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WDR45 Antibody: HRP

Rabbit Anti-Human WDR45 Polyclonal

Product Specifications

Background

WIPI-4 is a 360 amino acid protein containing three WD repeats. Existing as three alternatively spliced isoforms, WIPI-4 is ubiquitously expressed but found at highest levels in heart and skeletal muscle. WD repeat proteins are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Diseases associated with this gene include neurodegeneration with brain iron accululation 5 and 4.

Specifications

Detects ~40 kDa.

Product Name Alternative

Cancer, Autophagy, Cell Signaling, Apoptosis

UNSPSC

12352203

Gene ID

11152

Swiss Prot

Q9Y484

Accession Number

NP_001025067.1

Cellular Locus

0

Host

Rabbit

Species Reactivity

Human,Rat

Immunogen

Synthetic peptide from the C-terminal of Human WIPI4 (aa. 312-322)

Target

WDR45

Clonality

Polyclonal

Conjugation

HRP

Tissue Specificity

Ubiquitously expressed, with high expression in skeletal muscle and heart. Weakly expressed in liver and placenta. Expression is down-regulated in pancreatic and in kidney tumors.

Validated Applications

WB,IHC,ELISA

Purification

Peptide Affinity Purified

Concentration

1 mg/ml

Dilution

WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

73.64mM Carbonate, 54.55mM Ethanolamine, 45.45mM Cyanoborohydride, 18.18mM Sodium Hydroxide and 0.23mM Citrate in dH2O

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. http://www.genecards.org/cgi-bin/carddisp.pl?gene=WDR45 2. Strausberg R.L., et al. (2002) Proc Natl Acad Sci U S A. 99(26): 16899–16903. 3. Haack T.B., et al. (2012) Am J Hum Genet. 91(6): 1144–1149.

Product Datasheet

https://cdn.gentaur.com/products/400/4415303/datasheet/spc-651d-hrp.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4415303/msds/spc-651d-hrp.pdf

CAS Number

9007-83-4

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