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WDR45 Antibody: FITC

Rabbit Anti-Human WDR45 Polyclonal

Product Specifications

Background

WIPI-4 is a 360 amino acid protein containing three WD repeats. Existing as three alternatively spliced isoforms, WIPI-4 is ubiquitously expressed but found at highest levels in heart and skeletal muscle. WD repeat proteins are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Diseases associated with this gene include neurodegeneration with brain iron accululation 5 and 4.

Specifications

Detects ~40 kDa.

Product Name Alternative

Cancer, Autophagy, Cell Signaling, Apoptosis

UNSPSC

12352203

Gene ID

11152

Swiss Prot

Q9Y484

Accession Number

NP_001025067.1

Cellular Locus

0

Host

Rabbit

Species Reactivity

Human,Rat

Immunogen

Synthetic peptide from the C-terminal of Human WIPI4 (aa. 312-322)

Target

WDR45

Clonality

Polyclonal

Conjugation

FITC

Tissue Specificity

Ubiquitously expressed, with high expression in skeletal muscle and heart. Weakly expressed in liver and placenta. Expression is down-regulated in pancreatic and in kidney tumors.

Validated Applications

IHC,ICC/IF

Purification

Peptide Affinity Purified

Concentration

1 mg/ml

Dilution

WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

640.91mM DMSO, 136.36mM Ethanolamine, and 9.09mM Sodium Bicarbonate in 90.9% PBS

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. http://www.genecards.org/cgi-bin/carddisp.pl?gene=WDR45 2. Strausberg R.L., et al. (2002) Proc Natl Acad Sci U S A. 99(26): 16899–16903. 3. Haack T.B., et al. (2012) Am J Hum Genet. 91(6): 1144–1149.

Product Datasheet

https://cdn.gentaur.com/products/400/4415302/datasheet/spc-651d-fitc.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4415302/msds/spc-651d-fitc.pdf

CAS Number

9007-83-4

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