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ATG7 Antibody: HRP

Rabbit Anti-Human ATG7 Polyclonal

Product Specifications

Background

ATG7 in conjuction with ATG10, mediates the formation of the autophagosome when ATG12 is covalently bound to ATG5 and targets to autophagosome vesicles. It also activates ATG8, and is crucial for amino acid supply in neonates.

Specifications

Detects 77.9 kDa.

Product Name Alternative

Cancer, Apoptosis, Autophagy, Cardiovascular System, Heart

UNSPSC

12352203

Gene ID

10533

Swiss Prot

O95352

Accession Number

NP_001129503.2

Cellular Locus

Cytoplasm | Preautophagosomal Structure

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide from the N-terminal of Human ATG7

Target

ATG7

Clonality

Polyclonal

Conjugation

HRP

Tissue Specificity

Widely expressed, especially in kidney, liver, lymph nodes and bone marrow.

Validated Applications

WB,IHC,ELISA

Purification

Peptide Affinity Purified

Concentration

1 mg/ml

Dilution

WB (1:1000); ICC/IF (1:100); IHC (1:50); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

73.64mM Carbonate, 54.55mM Ethanolamine, 45.45mM Cyanoborohydride, 18.18mM Sodium Hydroxide and 0.23mM Citrate in dH2O

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Mizushima N., et al. (1998) J Biol Chem. 273: 33889-92. 2. Mizushima N., et al. (1998) Nature. 395: 395-8. 3. Suzuki K., et al. (2001) EMBO J. 20: 5971-81. 4. Tanida I., et al. (1999) Mol Biol Cell. 10: 1367-79. 5. Shintani T., et al. (1999) EMBO J. 18: 5234-41.

Product Datasheet

https://cdn.gentaur.com/products/400/4414628/datasheet/spc-610d-hrp.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4414628/msds/spc-610d-hrp.pdf

CAS Number

9007-83-4

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