Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

UVRAG Antibody: APC

Rabbit Anti-Human UVRAG Polyclonal

Product Specifications

Background

UVRAG (UV radiation resistance-associated gene) is associated with the Beclin-1/PI3KC3 complex and promotes PI3KC3 enzymatic activity and autophagy, while suppressing proliferation (1). Beclin-1 binding to UVRAG promotes both autophagosome maturation and endocytic trafficking (2). UVRAG is also a potential tumor suppressor protein with frameshift mutations observed in colon and gastric carcinomas (3-4). It is highly expressed in the brain, lung, kidney and liver.

Specifications

Predicted molecular weight at ~78.1kDa. Observed molecular weights in the 75-90kDa range.

Product Name Alternative

Cancer, Apoptosis, Autophagy, Cell Signaling, Epigenetics and Nuclear Signaling, Cardiovascular System, Heart

UNSPSC

12352203

Gene ID

7405

Swiss Prot

Q9P2Y5

Accession Number

NP_003360.2

Cellular Locus

Endosome | Lysosome | Endoplasmic reticulum | Nucleus | Chromosome | Centromere

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide from the mid-protein of human UVRAG

Target

UVRAG

Clonality

Polyclonal

Conjugation

APC

Validated Applications

IHC,ICC/IF

Purification

Peptide Affinity Purified

Concentration

1 mg/ml

Dilution

WB (1:1000); ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

95.64mM Phosphate, 2.48mM MES and 2mM EDTA

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Liang, C. et al. (2008) Nat Cell Biol. 10: 776-87. 2. Liang, C. et al. (2008) Nat Cell Biol. 10: 776-87. 3. Ionov, Y. et al. (2004) Oncogene. 23: 639-45. 4. Kim, M.S. et al. (2008) Hum Pathol. 39: 1059-63.

Product Datasheet

https://cdn.gentaur.com/products/400/4414519/datasheet/spc-606d-apc.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4414519/msds/spc-606d-apc.pdf

CAS Number

9007-83-4

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MMP13 Mouse Monoclonal Antibody [Clone 2D8]
E45M13976V-2 50 ul

MMP13 Mouse Monoclonal Antibody [Clone 2D8]

Ask
View Details
OR51A7 Peptide - C-terminal region
MBS3243719-01 0.1 mg

OR51A7 Peptide - C-terminal region

Ask
View Details
OR51A7 Peptide - C-terminal region
MBS3243719-02 5x 0.1 mg

OR51A7 Peptide - C-terminal region

Ask
View Details
hsa-miR-1911-5p Primers
MPH02270 150 μl / 10 μM

hsa-miR-1911-5p Primers

Ask
View Details
Monkey Collagen alpha-1 (XXV) chain (COL25A1) ELISA Kit
MBS7239164-01 48 Well

Monkey Collagen alpha-1 (XXV) chain (COL25A1) ELISA Kit

Ask
View Details
Monkey Collagen alpha-1 (XXV) chain (COL25A1) ELISA Kit
MBS7239164-02 96 Well

Monkey Collagen alpha-1 (XXV) chain (COL25A1) ELISA Kit

Ask
View Details