Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Amyloid Fibrils (OC) Antibody: FITC

Rabbit Anti-Human Amyloid Fibrils (OC) Polyclonal

Product Specifications

Background

Amyloid monomeric proteins can sometimes oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibres (1, 2). These include the amyloid-β peptide plaques and tau neurofibrillary tangles in senile plaques of Alzheimer's symptomology, the deposition of α-synuclein in the Lewy bodies of Parkinson's disease, and accumulation of polyglutamine-containing aggregates in Huntington's disease (2, 3).

Specifications

Recognizes generic epitopes common to many amyloid fibrils and fibrillar oligomers, but not prefibrillar oligomers or natively folded proteins. Expected to detect in Mouse and Rat based on species homology.

Product Name Alternative

Neuroscience, Cell Signaling, Cardiovascular System, Blood, Neurodegeneration, Alzheimer's Disease, Amyloid

UNSPSC

12352203

Cellular Locus

Membrane

Host

Rabbit

Species Reactivity

Human

Immunogen

Fibrils prepared from human amyloid beta 42 peptide

Target

Amyloid Fibrils (OC)

Clonality

Polyclonal

Conjugation

FITC

Validated Applications

IHC,ICC/IF

Purification

Protein A Purified

Dilution

WB (1:1000), IHC (1:100); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

640.91mM DMSO, 136.36mM Ethanolamine, and 9.09mM Sodium Bicarbonate in 90.9% PBS

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Glabe C.G. (2004) Trends Biochem Sci. 29(10): 542-547. 2. Kayed R., et al. (2004) J Bio. Chem. 279: 46363-46366. 3. Kayed R., et al. (2003) Science. 300(5618): 486-489.

Product Datasheet

https://cdn.gentaur.com/products/400/4414352/datasheet/spc-507d-fitc.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4414352/msds/spc-507d-fitc.pdf

CAS Number

9007-83-4

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Rat rno-miR-3566 miRNA Agomir
abx885103-01 5 nmol

Rat rno-miR-3566 miRNA Agomir

Ask
View Details
Rat rno-miR-3566 miRNA Agomir
abx885103-02 10 nmol

Rat rno-miR-3566 miRNA Agomir

Ask
View Details
Recombinant Shigella boydii serotype 18 Spermidine export protein MdtI (mdtI)
MBS7020147-01 0.02 mg

Recombinant Shigella boydii serotype 18 Spermidine export protein MdtI (mdtI)

Ask
View Details
Recombinant Shigella boydii serotype 18 Spermidine export protein MdtI (mdtI)
MBS7020147-02 0.1 mg

Recombinant Shigella boydii serotype 18 Spermidine export protein MdtI (mdtI)

Ask
View Details
Recombinant Shigella boydii serotype 18 Spermidine export protein MdtI (mdtI)
MBS7020147-03 5x 0.1 mg

Recombinant Shigella boydii serotype 18 Spermidine export protein MdtI (mdtI)

Ask
View Details
MYCBP, NT (MYCBP, AMY1, C-Myc-binding protein, Associate of Myc 1) (Azide free) (HRP)
MBS6323213-01 0.2 mL

MYCBP, NT (MYCBP, AMY1, C-Myc-binding protein, Associate of Myc 1) (Azide free) (HRP)

Ask
View Details