TCA1
TCA1 is a small molecule with activity against agent-susceptible and -resistant Mycobacterium tuberculosis (Mtb) . TCA1 inhibits enzymes involved in cell wall and molybdenum cofactor biosynthesis, such as DprE1 and MoeW[1].
Product Specifications
CAS Number
864941-32-2
UNSPSC
12352005
Hazard Statement
H319
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tca1.html
Purity
98.29
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NC1=C(C(NC(OCC)=O)=O)C=CS1)C2=NC3=CC=CC=C3S2
Molecular Formula
C16H13N3O4S2
Molecular Weight
375.42
Precautions
P264-P280-P305+P351+P338
References & Citations
[1]Feng Wang, et al. Identification of a small molecule with activity against drug-resistant and persistent tuberculosis. Proc Natl Acad Sci U S A. 2013 Jul 2;110 (27) :E2510-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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Med15 (Mediator of RNA Polymerase II Transcription Subunit 15, Mediator Complex Subunit 15, Positive Cofactor 2 glutamine/Q-rich-Associated Protein, PC2 glutamine/Q-rich-Associated Protein, mPcqap, Med15, Pcqap) (MaxLight 650)
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