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Aquaporin 3 Antibody: Biotin

Rabbit Anti-Rat Aquaporin 3 Polyclonal

Product Specifications

Background

Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins (1, 2). Aquaporin 3 is found in the basolateral cell membrane of principal collecting duct cells and provide a pathway for water to exit these cells (3). AQP3 gene expression is not regulated by vasopressin (4).

Specifications

Detects ~31.5kDa. May detect larger glycosylated bands ~35-50kDa.

Product Name Alternative

Neuroscience, Neurotransmission, Ion Channels, Aquaporins

UNSPSC

12352203

Gene ID

65133

Swiss Prot

P47862

Accession Number

NP_113891.1

Cellular Locus

Membrane

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Produced against the C-terminal peptide (Sequence N-CHLEQPPPSTEAENVKLAHMKHKEQI) of rat aquaporin 3

Target

Aquaporin 3

Clonality

Polyclonal

Conjugation

Biotin

Validated Applications

WB,IHC,ICC/IF |ELISA

Purification

Protein A Purified

Concentration

1 mg/ml

Dilution

WB (1:2000), IHC (1:200), ICC/IF (1:400); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

136.36mM Ethanolamine, and 9.55mM Sodium Bicarbonate in 95.45% PBS

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Gonen T., Walz T. (2006) Q. Rev. Biophys. 39(4): 361-396. 2. Knepper M.A. (1994) Proc Natl. Acad Sci. USA. 91(14): 6255-6258. 3. Sasaki S., Ishibashi K., and Marumo F. (1998) Annu Rev Physiol. 60: 199-220. 4. Dibas A.I., Mia A.J., Yorio T. (1998) Proc Soc Exp Med. 219(3): 183-199.

Product Datasheet

https://cdn.gentaur.com/products/400/4414271/datasheet/spc-504d-bi.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4414271/msds/spc-504d-bi.pdf

CAS Number

9007-83-4

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