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Aquaporin 1 Antibody: RPE

Rabbit Anti-Rat Aquaporin 1 Polyclonal

Product Specifications

Background

Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins (1, 2). Aquarporin 1 is a widely expressed water channel, found in the basolateral and apical plasma membranes of the proximal tubes, the descending loop of Henel and in the descending portion of the vasa recta. Additionally it is found in red blood cells, vascular endothelium, gastrointestinal tract, sweat glands and lungs. It is not regulated by vasopressin (3).

Specifications

Detects ~28.5kDa. May detect larger glycosylated bands ~35-50kDa.

Product Name Alternative

Neuroscience, Neurotransmission, Ion Channels, Aquaporins

UNSPSC

12352203

Gene ID

25240

Swiss Prot

P29975

Accession Number

NP_036910.1

Cellular Locus

Membrane

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Produced against the N-terminal peptide (sequence N-MASEFKKKLF) of rat Aquaporin 1

Target

Aquaporin 1

Clonality

Polyclonal

Conjugation

RPE

Validated Applications

WB,IHC,ICC/IF

Purification

Protein A Purified

Concentration

1 mg/ml

Dilution

WB (1:2000), IHC (1:200), ICC/IF (1:400); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

95.64mM Phosphate, 2.48mM MES and 2mM EDTA

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Gonen T., Walz T. (2006) Q. Rev. Biophys. 39(4): 361-396. 2. Knepper M.A. (1994) Proc Natl. Acad Sci. USA. 91(14): 6255-6258. 3. www.vivo.colostate.edu/hbooks/molecules/aquaporins.html

Product Datasheet

https://cdn.gentaur.com/products/400/4414231/datasheet/spc-502d-rpe.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4414231/msds/spc-502d-rpe.pdf

CAS Number

9007-83-4

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