What is the catalog number for P38 Antibody: PerCP?

The catalog number for P38 Antibody: PerCP is SPC-172D-PCP.

What sizes are available for P38 Antibody: PerCP?

P38 Antibody: PerCP is available in the following size(s): 100 µL.

Is P38 Antibody: PerCP in stock?

P38 Antibody: PerCP is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for P38 Antibody: PerCP?

The safety data sheet for P38 Antibody: PerCP is available here: https://www.stressmarq.com/wp-content/uploads/Antibody-MSDS.pdf.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

P38 Antibody: PerCP

Rabbit Anti-Human p38 Polyclonal

Product Specifications

Background

P38 is a member of the mitogen-activated protein kinase (MAPK) family, specifically involved in cellular responses to stress and inflammation. In the nervous system, p38 plays a pivotal role in regulating apoptosis, neuroinflammation, and synaptic plasticity—processes that are frequently dysregulated in neurodegenerative diseases. Upon activation by environmental and cellular stressors such as oxidative damage, cytokines, and UV radiation, p38 translocates to the nucleus where it modulates transcription factors and pro-apoptotic proteins. This leads to the release of cytochrome c, activation of caspase-3, and cleavage of PARP, promoting programmed cell death. In Alzheimer’s, Parkinson’s, and ALS, aberrant p38 signaling contributes to neuronal loss, glial activation, and neurodegenerative phenotypes. As a result, p38 has emerged as a therapeutic target for modulating neuroinflammation and preventing neuronal degeneration.

CAS Number

9007-83-4

Specifications

Detects ~43kDa.

Product Name Alternative

CSAID Binding protein 1, CSBP1, CSBP2, EXIP, MAP kinase MXI2, MAPkinase p38alpha, MAPK14, p38 ALPHA, p38 MAP kinase, p38 mitogen activated protein kinase, RK, SAPK 2A, Stress activated protein kinase 2A

UNSPSC

12352203

UN Code

Non-hazardous

Hazard Statement

Non-hazardous

Gene ID

1432

Swiss Prot

Q16539

Accession Number

NP_001306.1

Cellular Locus

Cytoplasm | Nucleus

Host

Rabbit

Species Reactivity

Human,Mouse,Rat,Bovine,Monkey,Rabbit,Pig,Dog,Hamster,Chicken,Sheep,Guinea pig

Immunogen

A 20 residue synthetic peptide based on the human p38 with the cysteine residue added and coupled to KLH

Target

p38

Clonality

Polyclonal

Conjugation

PerCP

Type

Polyclonal

Applications

WB | IHC | ICC/IF | IP

Validated Applications

WB,IHC,ICC/IF,ELISA

Field of Research

Cell Signaling | Post-translational Modifications | Phosphorylation | Cancer

Purification

Peptide Affinity Purified

Detection Range

A 1:1000 dilution of SPC-172 was sufficient for detection of p38 in 20 µg of HeLa cell lysate by ECL immunoblot analysis.

Concentration

1 mg/ml

Dilution

WB (1:1000), ICC/IF (1:100), IP (1:250) ; optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

95.46mM Phosphate, 2.48mM MES and 2mM EDTA

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Pearson G., et al (2001) Endocrine Reviews 22 (2) : 153-183. 2. Fan Y., et al (2007) Mol. Cells 23 (1) : 30-38. 3. Han J., et al. (1994) Science 265: 808-811. 4. Van L. A., et al. (2004) Faseb J. 18: 1946−1948. 5. Deng et al. (2003) Cell 115: 61-70. 6. Salojin K.V., et al. (2006) J Immunol. 176 (3) :1899-907. 7. Medicherla S., et al. (2006) J Pharmacol Exp Ther. 318 (1) : 99-107.

Shipping Conditions

Blue Ice or 4ºC

Storage Conditions

Conjugated antibodies should be stored according to the product label

Specificity