Secologanic acid

Secologanic acid is a secoiridoid glycoside. Secologanic acid inhibits NO production, the relative expression of AKT and p-AKT. Secologanic acid shows anti-inflammatory activity[1][2].

Product Specifications

CAS Number

[60077-46-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Akt; NO Synthase

Type

Natural Products

Related Pathways

Immunology/Inflammation; PI3K/Akt/mTOR

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/secologanic-acid.html

Purity

98.02

Solubility

H2O : 25 mg/mL (ultrasonic)

Smiles

O=C1C2=CO[C@@H](O[C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)[C@H](C=C)[C@]2([H])CC(O)O1

Molecular Formula

C16H22O10

Molecular Weight

374.34

Precautions

H302, H315, H319, H335

References & Citations

[1]Tamara L Meragelman, et al. Modified secoiridoid from Acicarpha tribuloides and inhibition of nitric oxide production in LPS-activated macrophages. Phytochemistry. 2006 Jul;67 (14) :1534-8.|[2]Guo X, et al. Network Pharmacology-Based Identification of Potential Targets of Lonicerae japonicae Flos Acting on Anti-Inflammatory Effects. Biomed Res Int. 2021 Sep 20;2021:5507003.